UNC0379 trifluoroacetate everine metabolite O-desmethyl Mebeverine acid Ganesha Rai

Name: UNC0379 trifluoroacetate everine metabolite O-desmethyl Mebeverine acid Ganesha Rai
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SKU: 87264258903
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SKU: 87264258903

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Description

Ganesha Rai

selective aurora a kinase inhibitor

SAR407899 (3 mg/kg

CK-1827452

medicine and commodity trade

UNC0379 trifluoroacetate everine metabolite O-desmethyl Mebeverine acid Ganesha RaiUNC0379 trifluoroacetate salt is a substrate competitive inhibitor of the lysine methyltransferase SETD8, the only known methyltransferase that catalyzes monomethylation of histone H4 lysine 20 (H4K20). HK420 methylation has been implicated in the regulation of a variety of biological processes including the DNA damage response. UNC0379 is selective for SETD8 over 15 other methyltransferases, with an IC50 value of 7. 3 M for SETD8 compared to IC50

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